Endometrial glandular proliferation and estrogen receptor content during the normal menstrual cycle

Endometrial glandular proliferation and estrogen receptor content during the normal menstrual cycle
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DOI:
10.1016/s0010-7824(96)00242-9
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发表时间:
1997-01-01
期刊:
影响因子:
2.9
通讯作者:
Farahmand, S
Farahmand, S
中科院分区:
医学3区
文献类型:
--
作者:
Felix, JC;Farahmand, S

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对35例正常经期绝经前妇女的子宫切除术标本进行了检查,以确定子宫内膜腺增生与雌激素受体含量的关系。患者分为卵泡期(20例)、黄体前期、排卵后1 ~ 5天(5例)和黄体中后期(10例)。根据mb -1的表达,增殖率在卵泡期(701个细胞/1000)在功能子宫内膜中最大,在黄体早期(327个细胞/1000)减少一半,在黄体中后期几乎停止(8个细胞/1000)(p
Hysterectomy specimens from 35 normally cycling premenopausal women were examined to determine the relationship of endometrial glandular proliferation to estrogen receptor content. The cases were divided into follicular phase (n = 20), early luteal phase, days 1-5 post ovulation (n = 5), and mid to late luteal phase (n = 10). Proliferation rates, as determined by MIB-1 expression, were maximal in the endometrial functionalis during the follicular phase (701 cells/1000), decreased by half during the early luteal phase (327 cells/1000), and virtually ceased during the mid to late luteal phase (8 cells/1000) (p