PRENATAL EXPOSURE TO METHYL MERCURY AMONG GREENLANDIC POLAR INUITS

PRENATAL EXPOSURE TO METHYL MERCURY AMONG GREENLANDIC POLAR INUITS
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DOI:
10.1080/00039896.1990.10118754
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发表时间:
1990-11-01
期刊:
ARCHIVES OF ENVIRONMENTAL HEALTH
影响因子:
--
通讯作者:
BOHM, J
BOHM, J
中科院分区:
其他
文献类型:
--
作者:
HANSEN, JC;TARP, U;BOHM, J

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1982年至1988年期间,在北格陵兰收集了因纽特妇女及其新生儿的37对血样。 分析了样本的全血总汞含量(总汞)和甲基汞含量(甲基汞)。 在母体血液中,80%的总汞被发现是甲基化的,而在脐带血中为98%。 母血与脐血中汞含量呈显著相关,母血与胎儿血中汞含量的平均比值为1.9。 脐带血中甲基汞浓度与母亲海洋食物摄入量密切相关。 84%的母亲血液中甲基汞浓度高于0.11 μ mol/l(23 μ g/l),这相当于世界卫生组织规定的临时可耐受摄入量限值。 这表明,大多数孕妇的甲基汞摄入量高得令人无法接受。
During the period 1982 to 1988, 37 paired samples of blood from Inuit women and their newborn children were collected in North Greenland. The samples were analyzed for whole blood content of total mercury (tot-Hg) and for content of methyl mercury (Me-Hg). In maternal blood, 80% of the tot-Hg was found to be methylated in contrast to 98% in cord blood. Concentrations of Me-Hg in maternal and cord blood were significantly correlated, and the mean ratio between fetal and maternal blood Me-Hg was 1.9. Concentrations of Me-Hg in cord blood were closely related to the marine food intake of the mothers. Eighty-four percent of the mothers had blood concentrations of Me-Hg above 0.11-mu-mol/l (23-mu-g/l), which corresponds to the provisional limit of tolerable intake set by the World Health Organization. This indicates that the majority of the pregnant women have an unacceptable high intake of methyl mercury.