Sense of coherence moderates the relationship between life stress and natural killer cell activity in healthy older adults.
Sense of coherence moderates the relationship between life stress and natural killer cell activity in healthy older adults.
复制标题
连贯感调节健康老年人的生活压力和自然杀伤细胞活性之间的关系。
DOI：
10.1037//0882-7974.14.4.552
复制
发表时间：
1999
影响因子：
3.7
通讯作者：
Lubaroff,DM
中科院分区：
文献类型：
--
作者：
Lutgendorf,SK;Vitaliano,PP;Tripp-Reimer,T;Harvey,JH;Lubaroff,DM
研究发现，一致性感 (SOC) 是老年人健康结果和生活满意度的有力预测指标。这项研究调查了 30 名健康老年人和 28 名年龄匹配的对照者预期自愿住房搬迁对情绪和免疫的影响，并检验了 SOC 是否会缓冲搬迁对自然杀伤 (NK) 细胞活性的影响。搬迁者在搬迁至集中生活设施前 1 个月完成评估并抽血；同时评估控制措施。与对照组相比，搬家者的积极情绪和NK活性降低，思维侵入性升高。积极情绪调节运动与 NK 活性的关系，而 SOC 调节这种关系。低 SOC 移动者的 NK 活性最差；高 SOC 驱动器的性能受到的影响较小。这些发现与 SOC 和积极情绪对面临压力的生活转变的老年人的免疫功能可能产生的有益作用一致。（PsycInfo 数据库记录 (c) 2022 APA，保留所有权利）
A sense of coherence (SOC) has been found to be a strong predictor of health outcomes and life satisfaction in older adults. This study investigated mood and immune effects of anticipated voluntary housing relocation in 30 healthy older adults and 28 age-matched controls and examined whether SOC would buffer effects of relocation on natural killer (NK) cell activity. Movers completed assessments and had blood drawn 1 month before relocation to congregate living facilities; controls were assessed concurrently. Compared with the control group, movers showed decreased positive mood and NK activity and elevated thought intrusion. Positive mood mediated the relationship of moving with NK activity, whereas SOC moderated this relationship. Low SOC movers had the poorest NK activity; that of high SOC movers was less compromised. These findings are consistent with possible salutogenic contributions of SOC and positive mood to immune function in older adults facing stressful life transitions.(PsycInfo Database Record (c) 2022 APA, all rights reserved)