The localization of radioantibodies in human brain tumors. II. Radioautography.

The localization of radioantibodies in human brain tumors. II. Radioautography.
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放射性抗体在人脑肿瘤中的定位。

DOI:
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发表时间:
1965
期刊:
影响因子:
11.2
通讯作者:
E. Day
E. Day
中科院分区:
医学1区
文献类型:
--
作者:
M. Mahaley;J. Mahaley;E. Day

文献摘要

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概述从11个脑瘤和邻近脑组织制备了125I放射自显影,这些脑瘤和邻近脑组织在颈内动脉注射抗胶质瘤-125I抗体几天后被活检。抗体的放射自显影与球蛋白-131I、RISA-131I、2-RISA-125I、新羟基-203汞和新羟基-197汞等非特异性脑扫描物质的放射自显影进行了比较。
Summary 125 I radioautographs were prepared from 11 brain tumors and adjacent brain tissue that had been biopsied several days after internal carotid infusion with anti-glioma- 125 I antibodies. Antibody localization, distinct from nonspecific localization, was noted in each of the 11. The radioautographs of antibody were compared with those of nonspecific brain-scanning substances including globulin- 131 I, RISA- 131 I, 2 RISA- 125 I, neohydrin- 203 Hg, and neohydrin- 197 Hg.