Increased catecholamine levels in urine in subjects exposed to road traffic noise - The role of stress hormones in noise research
Increased catecholamine levels in urine in subjects exposed to road traffic noise - The role of stress hormones in noise research
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DOI：
10.1016/s0160-4120(01)00030-7
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发表时间：
2001-06-01
影响因子：
11.8
通讯作者：
Ising, H
中科院分区：
文献类型：
--
作者：
Babisch, W;Fromme, H;Ising, H
在30-45岁的女性，其卧室和/或起居室面对不同交通量的街道，夜间尿中的儿茶酚胺排泄进行了研究。街道的交通量被用作噪声暴露的指标;肾上腺素和去甲肾上腺素浓度被评估为生理应激结果的指标。交通量和尿中去甲肾上腺素浓度之间的显着关联被发现与暴露的卧室（而不是客厅），表明更高的慢性生理唤醒噪声暴露的受试者相比，暴露较少。交通噪声干扰的主观测量与去甲肾上腺素水平呈正相关。然而，这只发现在关闭窗口不能减少感知的干扰，这表明个人应对机制的有效性的科目。在流行病学噪声研究中，应激激素是研究噪声、健康结果和效应调节剂之间的关联、机制和相互作用的有用指标。(C)2001爱思唯尔科技有限公司版权所有。
The nocturnal excretion of catecholamines in urine was studied in 30-45-year-old women whose bedroom and/or living room were facing streets of varying traffic volume. The traffic volume of the streets was used as an indicator of noise exposure; adrenaline and noradrenaline concentrations were assessed as indicators of the outcome of the physiological stress. Significant associations between traffic volume and noradrenaline concentrations in urine were found with regard to the exposure of the bedroom (not the living room), indicating a higher chronic physiological arousal in noise-exposed subjects as compared to less exposed. Subjective measures of disturbance due to traffic noise were positively correlated with the noradrenaline level. However, this was only found in subjects where closing the window could not reduce the perceived disturbance, which points to the effectiveness of individual coping mechanisms. Stress hormones are useful indicators to study associations, mechanisms, and interactions between noise, health outcomes, and effect modifiers in epidemiological noise research. (C) 2001 Elsevier Science Ltd. All rights reserved.