Physical exercise during pregnancy and the risk of preterm birth: A study within the Danish National Birth Cohort
Physical exercise during pregnancy and the risk of preterm birth: A study within the Danish National Birth Cohort
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DOI：
10.1093/aje/kwm364
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发表时间：
2008-04-01
影响因子：
5
通讯作者：
Andersen, Anne-Marie Nybo
中科院分区：
文献类型：
--
作者：
Juhl, Mette;Andersen, Per Kragh;Andersen, Anne-Marie Nybo
根据许多国家的建议，女性在怀孕期间应该进行体育锻炼，但支持这一建议的经验证据很少。作者本研究的目的是探讨怀孕期间的体育锻炼与早产风险之间的关系。前瞻性收集了 1996 年至 2002 年间丹麦国家出生队列中 87,232 名单胎孕妇的怀孕期间体育锻炼的自我报告数据。使用 Cox 回归分析分别计算了根据每周锻炼时间、锻炼类型和每周代谢当量小时的早产风险比。结果显示，与不锻炼者相比，近 40% 怀孕期间进行某种锻炼的女性早产风险降低（风险比 = 0.82，95% 置信区间：0.76、0.88），但没有发现剂量反应关系。这种关联不受运动类型的影响，并且当考虑到早产程度时，结果也没有改变。这些发现并不表明运动对早产风险有任何不利影响，因此与当前的建议并不矛盾。
According to many national recommendations, women should be physically active during pregnancy, but empirical evidence to support this recommendation is sparse. The authors' aim in this study was to examine the relation between physical exercise during pregnancy and the risk of preterm birth. Self-reported data on physical exercise during pregnancy were collected prospectively for 87,232 singleton pregnancies included in the Danish National Birth Cohort between 1996 and 2002. Hazard ratios for preterm birth according to hours of exercise per week, type of exercise, and metabolic equivalent-hours per week, respectively, were calculated using Cox regression analysis. Results showed a reduced risk of preterm birth among the almost 40% of women who engaged in some kind of exercise during pregnancy in comparison with nonexercisers (hazard ratio = 0.82, 95% confidence interval: 0.76, 0.88), but no dose-response relation was seen. The association was not affected by the type of exercise, and the results were not altered when the degree of preterm birth was taken into account. These findings do not indicate any adverse effects of exercise on the risk of preterm birth and therefore do not contradict current recommendations.