SUBSTANCE-P-IMMUNOREACTIVE AND CGRP-IMMUNOREACTIVE NERVES IN BONE
SUBSTANCE-P-IMMUNOREACTIVE AND CGRP-IMMUNOREACTIVE NERVES IN BONE
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DOI：
10.1016/0196-9781(88)90023-x
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发表时间：
1988-01-01
期刊：
影响因子：
3
通讯作者：
SCHULTZBERG, M
中科院分区：
文献类型：
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作者：
BJURHOLM, A;KREICBERGS, A;SCHULTZBERG, M
本研究证实P物质(SP)和降钙素基因相关肽(CGRP)免疫反应神经纤维存在于骨、骨髓、骨膜、滑膜和邻近骨的软组织中。这两种神经的分布是相似的，尽管CGRP阳性纤维一般更多。两种类型的神经都特别丰富，尤其是在骨膜板附近，在髌骨和骨膜的骨髓中，以及在骨膜中。血管周围也可见大量SP和CGRP免疫反应纤维。
The present study demonstrates the occurrence of substance P (SP)- and calcitonin gene related peptide (CGRP)-immunoreactive nerve fibers in bone, bone marrow, periosteum, synovial membrane and soft tissues adjacent to the bone. The distribution of the two types of nerves was similar, although the CGRP-positive fibres generally were more numerous. Both types of nerves were particularly abundant near the epiphyseal plate, in the bone marrow of patella and epiphyses, and in the periosteum. Many SP- and CGRP-immunoreactive fibres were also observed around blood vessels.