Enhanced accuracy in novel mirror drawing after repetitive transcranial magnetic stimulation-induced proprioceptive deafferentation
Enhanced accuracy in novel mirror drawing after repetitive transcranial magnetic stimulation-induced proprioceptive deafferentation
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DOI：
10.1523/jneurosci.1738-04.2004
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发表时间：
2004-10-27
影响因子：
5.3
通讯作者：
Miall, RC
中科院分区：
文献类型：
--
作者：
Balslev, D;Christensen, LOD;Miall, RC
当在视觉反馈扰动的条件下执行视觉引导动作时，例如，在一个实施例中，在镜子或摄像机中，视觉和本体感受信息之间存在空间冲突。最近的研究表明，没有本体感觉的受试者可以避免这种冲突，并表现出性能优势。在这项研究中，我们测试了重复经颅磁刺激（rTMS）诱导的传入神经阻滞是否可以提高正常受试者的镜像追踪技能。手轨迹误差在新的镜子绘制进行了比较，在两组受试者接受1 Hz rTMS的体感皮层对侧的手或假刺激。镜像追踪在rTMS后比假刺激后更准确。使用位置匹配的任务，我们证实，rTMS降低本体感觉敏锐度，这种减少是最大的线圈时，被放置在前顶叶网站。因此，它是可能的，rTMS，以提高运动性能的任务，涉及的视觉本体感受冲突，大概是通过减少兴奋性的躯体感觉皮质区，有助于感觉手的位置。
When performing visually guided actions under conditions of perturbed visual feedback, e. g., in a mirror or a video camera, there is a spatial conflict between visual and proprioceptive information. Recent studies have shown that subjects without proprioception avoid this conflict and show a performance benefit. In this study, we tested whether deafferentation induced by repetitive transcranial magnetic stimulation (rTMS) can improve mirror tracing skills in normal subjects. Hand trajectory error during novel mirror drawing was compared across two groups of subjects that received either 1 Hz rTMS over the somatosensory cortex contralateral to the hand or sham stimulation. Mirror tracing was more accurate after rTMS than after sham stimulation. Using a position-matching task, we confirmed that rTMS reduced proprioceptive acuity and that this reduction was largest when the coil was placed at an anterior parietal site. It is thus possible, with rTMS, to enhance motor performance in tasks involving a visuoproprioceptive conflict, presumably by reducing the excitability of somatosensory cortical areas that contribute to the sense of hand position.