Kaatsu training to enhance physical function of older adults with knee osteoarthritis: Design of a randomized controlled trial
Kaatsu training to enhance physical function of older adults with knee osteoarthritis: Design of a randomized controlled trial
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DOI：
10.1016/j.cct.2015.06.016
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发表时间：
2015-07-01
影响因子：
2.2
通讯作者：
Wu, Samuel S.
中科院分区：
文献类型：
--
作者：
Buford, Thomas W.;Fillingim, Roger B.;Wu, Samuel S.
随着美国人口老龄化，需要有效的干预措施来管理疼痛并维持患有骨关节炎（OA）的老年人的身体功能。骨骼肌无力是OA患者疼痛和功能下降的主要促成因素，因此需要改善肌肉力量的干预措施。高负荷抗阻运动是提高肌肉力量的最佳方法;然而，高压缩负荷通常会在OA患者中引起显著的关节疼痛。因此，需要低压缩负荷的干预措施，以提高肌肉力量，同时限制关节应力。这项研究正在调查的潜力，一个创新的培训模式，被称为Kaatsu，为此目的。Kaatsu涉及进行低负荷运动，而外部施加的压力部分限制了血液流向活跃的骨骼肌。这项随机、单盲试验的目的是评估长期Kaatsu训练对改善老年人骨骼肌力量和身体功能的有效性和可行性。年龄>= 60岁、身体受限和有症状的膝关节OA的参与者将被随机分配接受为期3个月的干预，包括（I）基于中心的中等负荷阻力训练，或（2）与总体工作量相匹配的Kaatsu训练。研究依赖性结局包括1）膝关节伸肌力量的变化，2）身体功能的客观指标，以及3）身体功能和疼痛的主观指标。这项研究将提供有关Kaatsu训练的治疗潜力的新信息，同时还通过评估参与者的安全性，不适感和持续参与干预的意愿来了解该范式的长期临床可行性。(C)2015 Elsevier Inc. All rights reserved.
As the U.S. population ages, efficacious interventions are needed to manage pain and maintain physical function among older adults with osteoarthritis (OA). Skeletal muscle weakness is a primary contributory factor to pain and functional decline among persons with OA, thus interventions are needed that improve muscle strength. High-load resistance exercise is the best-known method of improving muscle strength; however high-compressive loads commonly induce significant joint pain among persons with OA. Thus interventions with low-compressive loads are needed which improve muscle strength while limiting joint stress. This study is investigating the potential of an innovative training paradigm, known as Kaatsu, for this purpose. Kaatsu involves performing low-load exercise while externally-applied compression partially restricts blood flow to the active skeletal muscle. The objective of this randomized, single-masked pilot trial is to evaluate the efficacy and feasibility of chronic Kaatsu training for improving skeletal muscle strength and physical function among older adults. Participants aged >= 60 years with physical limitations and symptomatic knee OA will be randomly assigned to engage in a 3-month intervention of either (I) center-based, moderate-load resistance training, or (2) Kaatsu training matched for overall workload. Study dependent outcomes include the change in 1) knee extensor strength, 2) objective measures of physical function, and 3) subjective measures of physical function and pain. This study will provide novel information regarding the therapeutic potential of Kaatsu training while also informing about the long-term clinical viability of the paradigm by evaluating participant safety, discomfort, and willingness to continually engage in the intervention. (C) 2015 Elsevier Inc. All rights reserved.