Ultrasound monitoring of temperature change during radiofrequency ablation:: Preliminary in-vivo results
Ultrasound monitoring of temperature change during radiofrequency ablation:: Preliminary in-vivo results
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DOI：
10.1016/s0301-5629(01)00519-1
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发表时间：
2002-03-01
影响因子：
2.9
通讯作者：
Lee, FT
中科院分区：
文献类型：
--
作者：
Varghese, T;Zagzebski, JA;Lee, FT
射频（RF）消融是一种间质性局灶性消融治疗，可以经皮方式使用，并允许原位破坏肝肿瘤。然而，射频消融治疗后的局部肿瘤复发率高达34%至55%，这可能部分是由于无法准确监测被消融组织中的温度分布，以及无法可视化随后形成的坏死区（热损伤）。本文所述工作的目标是研究实时和体内监测发热和升温空间分布的方法，以更好地控制射频消融治疗期间的组织损伤程度。使用应用于在加热期间以离散间隔采集的RF超声（US）回波信号数据的互相关算法获得温度估计值。这些温度图用于显示初始温升并持续更新治疗区域的热图。目前使用射频消融穿刺针的尖头（尖齿）上的热传感器进行温度监测。然而，监测加热的空间分布对于控制所产生的组织损伤程度是必要的。（电子邮件：tvarghese@facstaff.wise.edu）（C）2002年世界医学生物学超声联合会。
Radiofrequency (RF) ablation is an interstitial focal ablative therapy that can be used in a percutaneous fashion and permits in situ destruction of hepatic tumors. However, local tumor recurrence rates after RF ablative therapy are as high as 34% to 55%, which may be due in part to the inability to monitor accurately temperature profiles in the tissue being ablated, and to visualize the subsequent zone of necrosis (thermal lesion) formed. The goal of the work described in this paper was to investigate methods for the real-time and in vivo monitoring of the spatial distribution of heating and temperature elevation to achieve better control of the degree of tissue damage during RF ablation therapy. Temperature estimates are obtained using a cross-correlation algorithm applied to RF ultrasound (US) echo signal data acquired at discrete intervals during heating. These temperature maps were used to display the initial temperature rise and to continuously update a thermal map of the treated region. Temperature monitoring is currently performed using thermosensors on the prongs (tines) of the RF ablation probe. However, monitoring the spatial distribution of heating is necessary to control the degree of tissue damage produced. (E-mail: tvarghese@facstaff.wise.edu) (C) 2002 World Federation for Ultrasound in Medicine Biology.