Nanozymes: Gold-nanoparticle-based transphosphorylation catalysts

Nanozymes: Gold-nanoparticle-based transphosphorylation catalysts
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DOI:
10.1002/anie.200460649
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发表时间:
2004-01-01
影响因子:
16.6
通讯作者:
Scrimin, P
Scrimin, P
中科院分区:
化学1区
文献类型:
--
作者:
Manea, F;Houillon, FB;Scrimin, P

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在纳米级金颗粒表面上的三氮杂环壬烷官能化硫醇的自组装提供了一个容易进入功能性金纳米颗粒的入口,其在与ZnII络合后,变成用于磷酸酯裂解的强力催化剂(参见方案)。由于它们的RNA酶样行为,它们被称为纳米酶。
The self-assembly of triazacyclonane-functionalized thiols on the surface of nanosize gold particles provides a facile entry to functional gold nanoparticles that, upon complexation with ZnII, turn into powerful catalysts for the cleavage of phosphate esters (see scheme). Because of their RNase-like behavior they are dubbed nanozymes.