Newer experimental methods for classifying depression. A report from the NIMH collaborative pilot study.
Newer experimental methods for classifying depression. A report from the NIMH collaborative pilot study.
复制标题
抑郁症分类的新实验方法。
DOI：
10.1001/archpsyc.1979.01780040089010
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发表时间：
1979
影响因子：
--
通讯作者：
G. Winokur
中科院分区：
文献类型：
--
作者：
N. Andreasen;G. Winokur
采用抑郁心理生物学协作研究，对83例在国家精神卫生研究所试点阶段确诊的抑郁症患者进行了两种新的基于家族史或病程的抑郁障碍分类方法的评价。基于家族史的第三种亚型，非家族性抑郁症，与Winokur和他的同事最初提出的两种亚型，单纯抑郁症和抑郁谱性疾病进行了比较。还比较了根据病程和先证性障碍对抑郁症进行分类的系统，即原发性抑郁症和继发性抑郁症。这些来自先导研究的数据表明，两种新的分类系统具有一定的预测性、构造性和内容效度，但在成为被接受的抑郁障碍分类方法之前，这两种系统都需要进一步的研究。
A total of 83 patients receiving diagnoses of major depressive disorder in the pilot phase of the National Institute of Mental Health Collaborative Study of the Psychobiology of Depression were used to evaluate two newer methods of classifying depressive disorders on the basis of family history or course. A third subtype based on family history, nonfamilial depression, was compared with the two subtypes originally proposed by Winokur and colleagues, pure depression and depression spectrum diseases. The system for classifying depressions on the basis of course and antecedent disorder, primary vs secondary depression, was also compared. These data from the pilot study indicate that two newer systems for classification have some predictive, construct, and content validity, but both are in need of further investigation before they become accepted methods for the classification of depressive disorders.