PET regional cerebral blood flow change during working and declarative memory: relationship with task performance.
PET regional cerebral blood flow change during working and declarative memory: relationship with task performance.
复制标题
工作和陈述性记忆期间 PET 局部脑血流变化：与任务表现的关系。
DOI：
10.1037//0894-4105.11.2.222
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发表时间：
1997
期刊：
影响因子：
2.4
通讯作者：
Gur,RE
中科院分区：
文献类型：
--
作者：
Ragland,JD;Glahn,DC;Gur,RC;Censits,DM;Smith,RJ;Mozley,PD;Alavi,A;Gur,RE
采用相同的刺激-反应方式，通过对比标准工作（威斯康星州卡片分类测验，WCST）和陈述性记忆（配对联想再认测验，PART）任务中局部脑血流量（rCBF）的变化，研究了工作记忆和陈述性记忆之间的功能和解剖学关系。在连续10分钟的正电子发射断层扫描15 O-水措施的rCBF的任务和静息基线管理30名参与者（16名男性，14名女性）。对于这两项任务，rCBF增加超过基线下额叶和枕颞区，与更一致的背外侧前额叶激活WCST比部分。在PART中观察到额外的眶额增加和背内侧减少。激活模式分歧时，性能被认为是。对于WCST，高性能激活背外侧和下额叶区域，而顶级部分执行激活枕颞区。这些结果表明，操作的额颞叶网络subserving这两种类型的记忆功能，成为更集中的性能增加。
Functional and anatomical relationships between working and declarative memory were investigated by contrasting regional cerebral blood flow (rCBF) change during standard working (Wisconsin Card Sorting Test, WCST) and declarative memory (Paired Associate Recognition Test, PART) tasks using identical stimulus–response modalities. The tasks and a resting baseline were administered to 30 participants (16 men, 14 women) during successive 10-min positron emission tomography 15 O-water measures of rCBF. For both tasks, rCBF increased over baseline in inferior frontal and occipitotemporal regions, with more consistent dorsolateral prefrontal activation for WCST than PART. Additional orbitofrontal increases and dorsomedial decreases were seen for the PART. Activation patterns diverged when performance was considered. For the WCST, high performers activated dorsolateral and inferior frontal regions, whereas top PART performers activated only the occipitotemporal region. These results suggest operation of a frontotemporal network subserving both types of memory function that becomes more focal as performance increases.