Chronically recording with a multi-electrode array device in the auditory cortex of an awake ferret
Chronically recording with a multi-electrode array device in the auditory cortex of an awake ferret
复制标题
DOI：
10.1016/j.jneumeth.2006.10.013
复制
发表时间：
2007-03-30
影响因子：
3
通讯作者：
Depireux, Didier A.
中科院分区：
文献类型：
--
作者：
Dobbins, Heather D.;Marvit, Peter;Depireux, Didier A.
已知麻醉抑制神经活动并抑制皮质-皮质相互作用和皮质输出。因此，重要的是记录清醒的动物，以便更好地了解神经反应的全动态范围。我们已经开发了一种用于在清醒的雪貂皮层中进行慢性多电极生理记录的制剂。本文讨论了几个优点和缺点的技术，以及用于克服潜在的并发症与慢性植入物在雪貂的程序。我们的解决方案非常适合特殊物种的要求，但也很容易推广到其他物种。(c)2006 Elsevier B. V.保留所有权利。
It is known that anesthesia depresses neural activity and inhibits cortico-cortical interactions and cortical output. Hence, it is important to record from awake animals in order to better understand the full dynamic range of neural responses. We have developed a preparation for chronic, multi-electrode physiological recording in the cortex of the awake ferret. This paper discusses several of the advantages and disadvantages of the technique as well as procedures used to overcome potential complications associated with chronic implants in the ferret. Our solutions are well suited to the special species requirements, yet are also easily generalizable to other species. (c) 2006 Elsevier B.V. All rights reserved.