Visuomotor adaptation during inactivation of the dentate nucleus
Visuomotor adaptation during inactivation of the dentate nucleus
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DOI：
10.1097/00001756-199904060-00025
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发表时间：
1999-04-06
期刊：
影响因子：
1.7
通讯作者：
Miall, RC
中科院分区：
文献类型：
--
作者：
Robertson, EM;Miall, RC
最近的实验表明，视觉运动适应的过程取决于视觉扭曲的引入方式。小脑被认为参与适应快速引入的视觉扭曲。然而，它在适应逐渐引入的扭曲方面的作用尚不清楚。我们测试了在猴子齿状核可逆失活过程中对突然或逐渐引入视觉扭曲的适应能力。在没有任何利多卡因输注和盐水输注期间，这两项任务都有显着的适应。然而，失活后，适应视觉扭曲的能力略有受损。在多次试验中引入视觉运动扭曲时，这种功能障碍很明显，这表明小脑对视觉适应的贡献不同，具体取决于所遇到的视觉运动障碍的类型。 NeuroReport 10:1029-1034 (C) 1999 Lippincott Williams & Wilkins。
RECENT experiments have suggested that the process of visuomotor adaptation depends on how a visual distortion is introduced. The cerebellum is thought to be involved in adapting to rapidly introduced visual distortions; however its role in adapting to a gradually introduced distortion is unknown. We tested adaptation to a sudden or a gradual introduction of a visual distortion, during reversible inactivation of a monkey's dentate nucleus. There was significant adaptation in both of these tasks without any lignocaine infusion and during saline infusions. However after inactivation the ability to adapt to either visual distortion was slightly impaired, This dysfunction was significant when the visuomotor distortion was introduced over several trials, suggesting that the cerebellum has a differential contribution to visual adaptation depending on the type of visuo-motor disturbance encountered. NeuroReport 10:1029-1034 (C) 1999 Lippincott Williams & Wilkins.