ISOLATION OF LANOSTANE-TYPE TRITERPENE ACIDS HAVING AN ACETOXYL GROUP FROM SCLEROTIA OF PORIA-COCOS
ISOLATION OF LANOSTANE-TYPE TRITERPENE ACIDS HAVING AN ACETOXYL GROUP FROM SCLEROTIA OF PORIA-COCOS
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DOI：
10.1016/0031-9422(95)00182-7
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发表时间：
1995-09-01
期刊：
影响因子：
3.8
通讯作者：
AKAHORI, A
中科院分区：
文献类型：
--
作者：
TAI, T;SHINGU, T;AKAHORI, A
The separation of lanostane-type triterpene acids carrying an acetoxyl group from sclerotia of Poria cocos (hoelen) was effectively achieved by means of preparative HPLC of the phthalimidomethyl esters followed by selective hydrolysis of the phthalimidomethyl ester groupings. By this method, three new triterpene acids were isolated together with pachymic and dehydropachymic acids, which are characteristic compounds of hoelen. The structures of three new compounds were determined to be 3-o-acetyl-16 alpha-hydroxytrametenolic acid, 3-o-acetyl-16 alpha-hydroxydehydrotrametenolic acid, and 3-epidehydropachymic acid, respectively, based on spectroscopic evidence.
