INTERDENTAL LOCALIZATION OF STREPTOCOCCUS-MUTANS AS RELATED TO DENTAL-CARIES EXPERIENCE
INTERDENTAL LOCALIZATION OF STREPTOCOCCUS-MUTANS AS RELATED TO DENTAL-CARIES EXPERIENCE
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DOI：
10.1128/iai.9.3.481-488.1974
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发表时间：
1974-01-01
影响因子：
3.1
通讯作者：
SKOBE, Z
中科院分区：
文献类型：
--
作者：
GIBBONS, RJ;DEPAOLA, PF;SKOBE, Z
为研究变形链球菌对牙面定植的一致性，以每周一次的间隔采样4个9~13岁儿童的近中磨牙表面。研究发现，含有可检测到的有机体水平的表面倾向于始终为正值，而没有可检测到的有机体水平的表面也倾向于保持这种状态。在所有被研究的表面中，在连续五周的采样中，81.7%的表面始终为阳性或一致为负。这些数据表明了这一点。变种人并不统一地定植在牙齿表面。观察到的一致的局部殖民模式表明了这一点。突变不容易在口腔内从一个牙面传播到另一个牙面。扫描电子显微镜观察表明，这是。突变后，单一感染的灵知能菌大鼠的牙齿作为离散的局部菌落定植，而奈氏放线菌菌株则以更普遍的方式定植。通过使用碘溶液对牙齿表面进行消毒的努力表明，这些人的牙齿表面没有受到感染。在治疗后，某些表面的突变可至少持续11至13周。通过可检测的比例OFS定植的牙齿表面的数量。研究发现，来自北卡罗来纳州夏洛特的18名既往龋齿经验较少的儿童的突变频率远远低于来自马萨诸塞州丹佛斯的20名有高龋齿经历的儿童。感染的牙面数。因此，变种人与这些人群的龋齿经历有很大的相似之处。
The consistency of colonization of tooth surfaces byStreptococcus mutanswas studied by sampling four approximal molar surfaces of 9- to 13-year-old children at weekly intervals. It was found that surfaces which harbored detectable levels of the organism tended to be consistently positive, whereas surfaces which were free of detectable levels of the organism also tended to remain that way. Of the total surfaces studied, 81.7% were either consistently positive or consistently negative throughout five consecutive weekly samplings. These data indicate thatS. mutansdoes not uniformly colonize the surfaces of teeth. The consistent localized patterns of colonization observed suggest thatS. mutansis not readily transmitted from one tooth surface to another within the mouth. Scanning electron microscope observations revealed thatS. mutanscolonized the teeth of monoinfected gnotobiotic rats as discrete localized colonies, whereas strains ofActinomyces naeslundiicolonized in a more generalized manner. Efforts to sterilize tooth surfaces by application of iodine solution indicated that the populations ofS. mutanson some surfaces could be affected for at least 11 to 13 weeks after treatment. The number of tooth surfaces colonized by detectable proportions ofS. mutanswas found to be far lower in a group of 18 children from Charlotte, N.C., with a low past caries experience than in 20 children from Danvers, Mass., with a high caries experience. The number of tooth surfaces infected withS. mutanstherefore strongly paralleled the caries experience of these populations.