Occupational physical activity in relation to risk of cardiovascular mortality: The Japan Collaborative Cohort Study for Evaluation for Cancer Risk (JACC Study)

Occupational physical activity in relation to risk of cardiovascular mortality: The Japan Collaborative Cohort Study for Evaluation for Cancer Risk (JACC Study)
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DOI:
10.1016/j.ypmed.2016.06.008
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发表时间:
2016-08-01
影响因子:
5.1
通讯作者:
Tamakoshi, Akiko
Tamakoshi, Akiko
中科院分区:
医学2区
文献类型:
--
作者:
Hayashi, Rie;Iso, Hiroyasu;Tamakoshi, Akiko

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我们研究了日本人群中职业性体力活动(OPA)模式与心血管疾病(CVD)死亡率之间的关系。一项基于社区的前瞻性队列研究对66,161名年龄在40-79岁之间、基线(1988-1990年)没有心血管疾病或癌症病史的男性和女性进行了跟踪,直到2009年。OPA分为四种类型:以坐、坐和站(坐/站)为主,以站和站(站/站)为主,站和走(站/走)为主。在中位数19.2年的随访中,登记了3728例心血管疾病死亡。与大多数坐着的OPA相比,站立/行走的OPA与所有受试者的心血管死亡风险并不相关,但在超重个体中,它与心血管死亡风险降低20%相关(体重指数=25 kg/m(2))。与大多数坐着的OPA相比,站立OPA与心血管疾病死亡的风险高出约20%,特别是在超重或运动量较少的人(
We examined the association between patterns of occupational physical activity (OPA) and mortality from cardiovascular disease (CVD) in a Japanese population. A community-based, prospective cohort of 66,161 men and women aged 40-79 years without a history of CVD or cancer at baseline (1988-1990) was followed until 2009. OPA was divided into four types: mostly sitting, sitting and standing (sitting/standing), mostly standing, and standing and walking (standing/walking). During follow-up for a median of 19.2 years, 3728 deaths from CVD were registered. Compared with mostly sitting OPA, standing/walking OPA was not associated with a reduced risk of CVD mortality for all subjects, but it was associated with a 20% lower risk of CVD mortality among overweight individuals (body mass index = 25 kg/m(2)). Compared with mostly sitting OPA, mostly standing OPA was associated with an approximately 20% higher risk of CVD mortality, especially among overweight individuals or those with lower exercise (