Catalytic enantioselective O-H insertion reactions
Catalytic enantioselective O-H insertion reactions
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DOI：
10.1021/ja0607739
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发表时间：
2006-04-12
影响因子：
15
通讯作者：
Fu, GC
中科院分区：
文献类型：
--
作者：
Maier, TC;Fu, GC
首次提出了催化对映体插入O-−氢键的有效方法。具体地说，铜/双氮杂二茂铁催化剂以高产率和良好的EE将2-三甲基硅乙醇等醇与α-芳基-α-重氮酯偶联。
The first effective method for catalytic enantioselective insertions into O−H bonds has been developed. Specifically, a copper/bisazaferrocene catalyst couples alcohols such as 2-trimethylsilylethanol with α-aryl-α-diazo esters in high yield and good ee.