Effect of tooth loss and nutritional status on outcomes after ischemic stroke
Effect of tooth loss and nutritional status on outcomes after ischemic stroke
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DOI：
10.1016/j.nut.2019.110606
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发表时间：
2020-03-01
期刊：
影响因子：
4.4
通讯作者：
Maruyama, Hirofumi
中科院分区：
文献类型：
--
作者：
Shiga, Yuji;Nezu, Tomohisa;Maruyama, Hirofumi
目的：牙齿脱落与营养不良密切相关，增加了心血管疾病的风险。本研究的目的是检查牙齿脱落，营养状况和中风outcomes.Methods之间的联系：我们回顾性分析了195例连续急性缺血性中风患者的牙齿脱落进行评估。牙齿脱落分为轻度或重度。使用控制营养状况（CONUT）评分评估营养状况。一个差的神经功能的结果被定义为3至6分的改良兰金量表在3个月后中风onset. Results的评分为0至2被定义为一个良好的outcome.Results：一个显着的相关性，观察到牙齿脱落和CONUT得分在入院（rho = 0.156，P = 0.034）。预后差的患者有较高的CONUT评分（P < 0.001）和较高的严重牙齿脱落频率（P= 0.025）。在多变量分析中，严重的牙齿脱落（优势比[OR]，3.93; 95%置信区间[CI]，1.31-11.8）和CONUT评分（OR，1.33; 95% CI，1.02-1.74）与不良卒中预后独立相关。严重的牙齿脱落和较高的CONUT评分与不良卒中结局独立相关。(C)2019爱思唯尔公司All rights reserved.
Objectives: Tooth loss, closely associated with malnutrition, increases the risk for cardiovascular disease. The aim of this study was to examine the link between tooth loss, nutritional status, and stroke outcomes.Methods: We retrospectively analyzed 195 consecutive patients with acute ischemic stroke who were evaluated for tooth loss. Tooth loss was classified as mild or severe. Nutritional status was evaluated using the Controlling Nutritional Status (CONUT) score. A poor neurologic outcome was defined as a score of 3 to 6 on the modified Rankin Scale at 3 mo post-stroke onset; a score of 0 to 2 was defined as a good outcome.Results: A significant correlation was observed between tooth loss and the CONUT score at admission (rho = 0.156; P = 0.034). Patients with poor outcomes had higher CONUT scores (P < 0.001) and a greater frequency of severe tooth loss (P= 0.025). On multivariate analysis, severe tooth loss (odds ratio [OR], 3.93; 95% confidence interval [CI], 1.31-11.8) and the CONUT score (OR, 1.33; 95% CI, 1.02-1.74) were independently associated with poor stroke outcomes.Conclusions: Nutritional status was associated with tooth loss among patients with acute ischemic stroke. Severe tooth loss and a higher CONUT score were independently associated with poor stroke outcomes. (C) 2019 Elsevier Inc. All rights reserved.