Electrophysiologic effects of surgical isolation of the right ventricle.
Electrophysiologic effects of surgical isolation of the right ventricle.
复制标题
右心室手术隔离的电生理效应。
DOI：
10.1016/s0003-4975(10)61838-3
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发表时间：
1986
期刊：
影响因子：
--
通讯作者：
Cox,JL
中科院分区：
文献类型：
--
作者：
DamianoJr,RJ;Asano,T;Smith,PK;FergusonJr,TB;DouglasJr,JM;Cox,JL
在10只犬中进行了整个右心室游离壁的手术隔离，以评价手术对各种电生理测量的影响。通过确定右心室电活动未传导至心脏的其余部分以及心房或左心室中的电活动未传导至右心室，确认右心室的完全手术隔离。右心室隔离不会导致右心室或左心室起搏阈值、右心室或左心室的有效不应期或右心室游离壁传导时间发生变化。此外，从右心房到左心室的正常传导时间术前为139 ± 5 msec（平均值±标准误），术后为135 ± 5 msec（p不显著），表明右心室隔离不会改变心房到左心室的同步性。然而，在隔离后，10只动物中有9只的右心室不能发生电纤维化，这一发现可能对控制慢性、危及生命的室性快速性心律失常的外科手术的未来发展具有重要意义。
Surgical isolation of the entire right ventricular free-wall was performed in ten dogs to evaluate the effects of the procedure on a variety of electrophysiologic measurements. Complete surgical isolation of the right ventricle was confirmed by determining that right ventricular electrical activity was not conducted to the remainder of the heart and that electrical activity in the atria or left ventricle did not conduct to the right ventricle. Right ventricular isolation caused no change in right ventricular or left ventricular pacing thresholds, in effective refractory periods of the right ventricle or left ventricle, or in right ventricular free-wall conduction time. Moreover, the normal conduction time from the right atrium to the left ventricle was 139 ± 5 msec (mean ± standard error) preoperatively and 135 ± 5 msec postoperatively (pis not significant), showing that atrial-to-left ventricular synchrony was unaltered by isolation of the right ventricle. However, following isolation, the right ventricle could not be electrically fibrillated in 9 of 10 animals, a finding that may have important implications in the future development of surgical procedures to control chronic, life-threatening ventricular tachyarrhythmias.