Synthesis of a key precursor for orienticin C and model study on ruthenium-mediated macrocyclization.
Synthesis of a key precursor for orienticin C and model study on ruthenium-mediated macrocyclization.
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DOI：
10.1021/jo702245z
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发表时间：
2008-01
期刊：
影响因子：
--
通讯作者：
A. Pearson;Diana V. Ciurea
中科院分区：
文献类型：
--
作者：
A. Pearson;Diana V. Ciurea
A tripeptido--arene--ruthenium complex was prepared as a key precursor for the projected synthesis of orienticin C, demonstrating that the cyclopentadienylruthenium moiety can be attached to a chloroarene in the presence of multiple functionality. The ruthenium-mediated intramolecular SNAr reaction for formation of the required diaryl ether linkage was successfully tested on a model system.
