STUDIES ON RNA FROM AVIAN MYELOBLASTOSIS VIRUS
STUDIES ON RNA FROM AVIAN MYELOBLASTOSIS VIRUS
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DOI：
10.1016/0042-6822(69)90313-4
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发表时间：
1969-01-01
期刊：
影响因子：
3.7
通讯作者：
ERIKSON, RL
中科院分区：
文献类型：
--
作者：
ERIKSON, RL
对禽成髓细胞病病毒的RNA进行了纯化，并对其部分特性进行了检测。从病毒中分离出两种RNA成分。根据RNA的甲基化量和它的碱基比率，在4秒时沉淀的小成分似乎与宿主细胞转移RNA相似。基于沉降特性，大组分表现为高分子量单链RNA，显然不会甲基化。然而，当该组分被加热到70°以上时，它解离成35s组分，在适当的条件下，这是唯一可检测到的分解产物。
RNA from avian myeloblastosis virus was purified and some of its properties were examined. Two RNA components were isolated from the virus. Based on the amount of methylation of the RNA and on its base ratios the small component, which sediments at 4 S, appears to be similar to host cell transfer RNA. The large component behaves like a high molecular weight single-stranded RNA based on sedimentation properties and is apparently not methylated. However, when this component is heated above 70° it dissociates to a 35 S component(s) which under appropriate conditions is the only detectable breakdown product.