Discovering up-regulated VEGF-C expression in swine umbilical vein endothelial cells by classical swine fever virus Shimen.
Discovering up-regulated VEGF-C expression in swine umbilical vein endothelial cells by classical swine fever virus Shimen.
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发现猪瘟病毒石门上调猪脐静脉内皮细胞中 VEGF-C 的表达。
DOI:
10.1186/1297-9716-45-48
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发表时间:
2014-04-23
影响因子:
4.4
通讯作者:
Li H
中科院分区:
文献类型:
--
作者:
Ning P;Zhang Y;Guo K;Chen R;Liang W;Lin Z;Li H
Infection of domestic swine with the highly virulent Shimen strain of classical swine fever virus causes hemorrhagic lymphadenitis and diffuse hemorrhaging in infected swine. We analyzed patterns of gene expression for CSFV Shimen in swine umbilical vein endothelial cells (SUVECs). Transcription of the vascular endothelial growth factor (VEGF) C gene (VEGF-C) and translation of the corresponding protein were significantly up-regulated in SUVECs. Our findings suggest that VEGF-C is involved in mechanisms of acute infection caused by virulent strains of CSFV.
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影响因子:
7
作者:
Gibbons, FD;Roth, FP
通讯作者:
Roth, FP
影响因子:
4.8
作者:
Saaristo, A;Veikkola, T;Alitalo, K
通讯作者:
Alitalo, K
DOI:
10.1080/10739680802095964
发表时间:
2008-11
期刊:
Microcirculation (New York, N.Y. : 1994)
影响因子:
--
作者:
Mac Gabhann F;Popel AS
通讯作者:
Popel AS
影响因子:
50.3
作者:
Eriksson, A;Cao, RH;Cao, YH
通讯作者:
Cao, YH
影响因子:
5.4
作者:
Savory, LJ;Stacker, SA;Mercer, AA
通讯作者:
Mercer, AA