Ambulatory anorectal physiology in patients following restorative proctocolectomy for ulcerative colitis: Comparison with normal controls
Ambulatory anorectal physiology in patients following restorative proctocolectomy for ulcerative colitis: Comparison with normal controls
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溃疡性结肠炎恢复性直肠结肠切除术后患者的动态肛门直肠生理学：与正常对照的比较
DOI：
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发表时间：
1990
影响因子：
9.6
通讯作者：
N. McC. Mortensen
中科院分区：
文献类型：
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作者：
R. Miller;W. Orrom;G. Duthie;D. Bartolo;N. McC. Mortensen
本研究的目的是测定溃疡性结肠炎的恢复性直肠切除术后回肠肛管W袋池的测压活动，并与正常对照组进行比较。共进行了31项研究；有15名对照组(中位年龄52岁(范围29-80岁)，10名男性，5名女性)和16名眼袋患者(中位年龄40岁(28-52岁)，13名男性，3名女性)。用微型换能器导管测量肛门中括约肌压力和直肠压力。这些信号被数字化并记录在便携式电子存储器中，以供以后计算机显示和分析。该系统允许在完全行走的情况下对患者进行最小限度的限制研究。正常对照组采样次数(直肠压力、⩾括约肌压力)、有无排气和排气次数分别为7(1-41)次/h、3(1-7)次/h和1(0-3·5)次/h，而腹袋组分别为0(0-3)次/h、0(0-1)次/h和0(0-1)次/h(P<0·001)。与正常受试者肛门直肠的高度动态特性相比，有袋子的患者活动很少。有12次出现眼袋充盈感觉和排便欲望，其中6次与眼袋压力升高超过20毫米汞柱有关。一名患者夜间有污垢，这是唯一一名患者注意到频繁的眼袋收缩。结果表明，回肠肛袋运动通常是静止的，这组患者的尿失禁可能与回肠肛袋活动增加有关。
The purpose of this study was to determine the manometric activity of ileoanal W pouch reservoirs following restorative proctocolectomy for ulcerative colitis and to compare the results with normal controls. Thirty‐one studies were carried out; there were 15 controls (median age 52 years (range 29–80 years), 10 men, 5 women) and 16 pouch patients (median age 40 years (range 28–52 years), 13 men, 3 women). Mid‐anal sphincter pressure and ‘rectal’ pressure were measured with a microtransducer catheter. The signals were digitalized and recorded in a portable electronic memory for later computer display and analysis. The system allowed the study of patients with minimal constraints while fully ambulant. The frequency of sampling (rectal pressure ⩾ sphincter pressure), sensation of flatus present and flatus being passed were 7(1–41), 3(1–7) and 1(0–3·5)per hour in the normal controls and 0(0–3), 0(0–1) and 0(0‐1) respectively per hour in the pouch patients (P<0·001). Compared with the highly dynamic nature of the anorectum in normal subjects the patients with a pouch had very little activity. The sensation of pouch filling and the desire to defaecate were noted on 12 occasions and in six were associated with a rise in pouch pressure greater than 20 mmHg. One patient had nocturnal soiling and this was the only patient in whom frequent pouch contractions were noted. The results suggest that ileoanal pouch motility is usually quiescent and that incontinence in this group may be related to increased pouch activity.
回肠贮袋-肛门吻合术后的肛门和新直肠功能。
影响因子：
9
作者：
Stryker,SJ;Kelly,KA;Phillips,SF;Dozois,RR;BeartJr,RW
通讯作者：
BeartJr,RW