Ruthenium-catalyzed propargylic reduction of propargylic alcohols with silanes
Ruthenium-catalyzed propargylic reduction of propargylic alcohols with silanes
复制标题
DOI：
10.1002/anie.200601181
复制
发表时间：
2006-01-01
影响因子：
16.6
通讯作者：
Sato, Mitsunobu
中科院分区：
文献类型：
--
作者：
Nishibayashi, Yoshiaki;Shinoda, Akira;Sato, Mitsunobu
已知许多过渡金属络合物促进炔与硅烷的氢化硅烷化以得到相应的乙烯基硅烷，其是有机合成中的通用结构单元。[1]高立体和区域选择性的炔与硅烷的硅氢加成反应是有机合成中的一个重要课题。[1]过渡金属催化的硅氢加成反应的选择性取决于催化剂、底物、硅烷和溶剂的性质。[2，3]最近，Trost及其同事报道了从广泛的α-乙烯基硅烷中高度选择性地制备α-乙烯基硅烷的方法。
A number of transition-metal complexes are known to promote the hydrosilylation of alkynes with silanes to give the corresponding vinyl silanes, which are versatile building blocks in organic synthesis.[1] The development of highly stereo-and regioselective hydrosilylation reactions of alkynes with silanes is an important subject in organic synthesis.[1] The selectivity in transition-metal-catalyzed hydrosilylation depends on the nature of catalysts, substrates, silanes, and solvents.[2, 3] Recently, Trost and co-workers reported a highly selective preparation of α-vinyl silanes from a wide range of