INDICATIONS FOR EXAMINATION OF SPONTANEOUS-ABORTION SPECIMENS - A REASSESSMENT
INDICATIONS FOR EXAMINATION OF SPONTANEOUS-ABORTION SPECIMENS - A REASSESSMENT
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DOI：
10.1016/0002-9378(95)90616-9
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发表时间：
1995-11-01
影响因子：
9.8
通讯作者：
HORGER, EO
中科院分区：
文献类型：
--
作者：
WOLF, GC;HORGER, EO
根据滋养层细胞培养、超声检查和染色体分析的最新技术进步，对反复妊娠丢失的临床评估进行评估。使用基于核型结果的算法，成本效益计算证实，如果强调对反复流产标本进行核型分析的政策，每个患者平均可以节省1099.47美元。据估计，在45%到70%的此类病例中，可以确定特定的染色体原因。应该做出更协调的努力，培养反复妊娠损失的滋养层组织；这样的政策将导致情感和经济回报。
The clinical evaluation of recurrent pregnancy loss is assessed in light of recent technical advances in trophoblast culture, ultrasonography, and chromosome analysis. With an algorithm based on karyotype results, cost-benefit calculations confirm that an average savings of $1099.47 per patient could be achieved if a policy of karyotype analysis of recurrent abortion specimens was emphasized. It is estimated that a specific chromosomal cause could be identified in 45% to 70% of such cases. A more concerted effort should be made to culture trophoblast tissue from recurrent pregnancy losses; such a policy would result in both emotional and financial rewards.