Biology of the relaxin-like factor (RLF).
Biology of the relaxin-like factor (RLF).
复制标题
松弛素样因子（RLF）的生物学。
DOI：
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复制
发表时间：
1997
期刊：
影响因子：
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通讯作者：
R. Ivell
中科院分区：
文献类型：
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作者：
R. Ivell
松弛素样因子（RLF）是胰岛素-IGF-松弛素激素和生长因子家族的新成员。也被称为Leydig细胞胰岛素样因子（Ley-I-L），这种肽和编码它的mRNA似乎在睾丸的Leydig细胞中大量表达。然而，它也产生于一些物种的卵巢中的卵泡膜细胞和周期和妊娠的黄体中。RLF基因转录本在整个牛雌性生殖道和下丘脑中的表达水平低得多。虽然数据有限，但RLF似乎代表了一种新的分化相关因子，具有与雄性和雌性哺乳动物生殖生理学相关的特定功能。
The relaxin-like factor (RLF) is a novel member of the insulin-IGF-relaxin family of hormones and growth factors. Also known as the Leydig cell insulin-like factor (Ley-I-L), this peptide and the mRNA encoding it appear to be expressed in very large quantities in the Leydig cells of the testis. However, it is also produced in the ovary of a number of species in both follicular theca cells and in the corpus luteum of the cycle and pregnancy. RLF gene transcripts have been identified at a much lower level of expression throughout the bovine female reproductive tract and also in the hypothalamus. Although data are limited, it would appear that RLF represents a new differentiation-related factor with specific functions linked to reproductive physiology in male and female mammals.
人间质胰岛素样 (hLEY I-L) 基因在黄体和滋养层中表达。
DOI：
10.1210/jcem.80.2.7852540
发表时间：
1995
期刊：
The Journal of clinical endocrinology and metabolism.
影响因子：
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作者：
Tashima,LS;Hieber,AD;Greenwood,FC;Bryant-Greenwood,GD
通讯作者：
Bryant-Greenwood,GD