Low plasma zinc and iron in pica.

Low plasma zinc and iron in pica.
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DOI:
10.1007/bf02723740
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发表时间:
2003-02-01
影响因子:
4.3
通讯作者:
Nath, R.
Nath, R.
中科院分区:
医学4区
文献类型:
--
作者:
Singhi, Sunit;Ravishanker, R.;Nath, R.

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目的:为探讨微量元素在异食癖发病中的作用,特别是锌、铁元素,我们用原子吸收分光光度计测定了31例异食癖患儿血浆铁、锌、钙、镁和血铅的含量(Pica组)和60名年龄、性别和营养相匹配的对照组(对照组)在三级护理教学医院门诊设置的观察性病例和对照研究中。研究方法:将每组的数据按血红蛋白水平9 g/dl进一步分层,分别分为两个亚组pica-1和pica-2,以及对照组1和对照组2,以控制缺铁性贫血的混杂效应。结果:异食症患儿血浆铁水平(平均值± SD)为42.7 ± 9.2 mg/dl,比正常对照组(51.5 ± 10.0 mg/dl,P <0.01)低20%。
Objective: To determine role of trace elements in causation of pica with specific reference to zinc and iron we studied plasma levels of iron (Fe), Zinc (Zn), calcium (Ca) and magnesium (Mg) and blood lead (Pb) levels by atomic absorption spectrophotometer in 31 children with pica (Pica Group) and 60 controls matched for age, sex and nutrition (Control Group) in an observational case and control study in the settings of outpatient clinic of a tertiary care, teaching hospital. Methods: Data from each group were further stratified by hemoglobin level 9 g/dl into two subgroups pica-1 and pica-2, and control-1 and control-2 respectively, to control for confounding effect of iron deficiency anemia. Results: The plasma Fe level (mean +- SD) in children with pica (42.7 +- 9.2) mg/dl) was about 20% lower than that in controls (51.5 +- 10.0 mg/dl, p