The plaque hypothesis: understanding mechanisms of plaque progression and destabilization, and implications for clinical management.
The plaque hypothesis: understanding mechanisms of plaque progression and destabilization, and implications for clinical management.
复制标题
斑块假说：了解斑块进展和不稳定的机制以及对临床管理的影响。
DOI：
10.1097/hco.0000000000001077
复制
发表时间：
2023
影响因子：
2.3
通讯作者：
Stone,PeterH
中科院分区：
文献类型：
--
作者：
Ahmed,MonaE;Hakim,Diaa;Stone,PeterH
局部斑块形态、血流动力学模式和内部斑块成分构成高危特征，可能位于冠状动脉斑块的整个过程中，包括限流区和非限流区。为了使冠状动脉介入治疗具有最佳的临床效果，将其应用于风险最高的斑块区域(S)至关重要。
Local plaque topography, hemodynamic patterns, and internal plaque constituents constitute high-risk features that may be located along the entire course of the coronary plaque, including both flow-limiting and nonflow-limiting regions. For coronary interventions to have optimal clinical impact, it will be critical to direct their application to the plaque area (s) at highest risk.