Effects of prenatal exposure to air pollution on preeclampsia in Shenzhen, China
Effects of prenatal exposure to air pollution on preeclampsia in Shenzhen, China
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中国深圳产前空气污染暴露对先兆子痫的影响
DOI：
10.1016/j.envpol.2018.02.010
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发表时间：
2018-06-01
影响因子：
8.9
通讯作者：
Huang, Cunrui
中科院分区：
文献类型：
--
作者：
Wang, Qiong;Zhang, Huanhuan;Huang, Cunrui
环境空气污染对孕妇的影响在中国备受关注。然而，人们对空气污染和先兆子痫之间的关系知之甚少，气象条件的潜在影响也没有得到评估。本研究旨在评估产前空气污染暴露对子痫前期的影响，并探讨温度和湿度是否会改变这种影响。我们进行了一项回顾性队列研究，该研究基于2005年至2012年间中国深圳出生登记系统中的121万单胎新生儿。颗粒物日平均测量值第95百分位。我们还发现，空气污染对子痫前期的影响在秋冬季节强于春夏季节。这是首次研究气象因素对空气污染与子痫前期关系的调节作用。研究结果表明，在中国深圳，产前暴露于PM10和SO2会增加子痫前期的风险，并且这种影响可能会受到湿度的影响。孕妇应限制接触空气污染，特别是在潮湿时期。(C) 2018 Elsevier Ltd.版权所有。
The impact of ambient air pollution on pregnant women is a concern in China. However, little is known about the association between air pollution and preeclampsia and the potential modifying effects of meteorological conditions have not been assessed. This study aimed to assess the effects of prenatal exposure to air pollution on preeclampsia, and to explore whether temperature and humidity modify the effects. We performed a retrospective cohort study based on 1.21 million singleton births from the birth registration system in Shenzhen, China, between 2005 and 2012. Daily average measurements of particulate matter 95th percentile. We also found that air pollution effects on preeclampsia in autumn/winter seasons were stronger than those in the spring/summer. This is the first study to address modifying effects of meteorological factors on the association between air pollution and preeclampsia. Findings indicate that prenatal exposure to PM10 and SO2 increase preeclampsia risk in Shenzhen, China, and the effects could be modified by humidity. Pregnant women should limit air pollution exposure, particularly during humid periods. (C) 2018 Elsevier Ltd. All rights reserved.