GROUP-C BETA-HEMOLYTIC STREPTOCOCCAL BACTEREMIA
GROUP-C BETA-HEMOLYTIC STREPTOCOCCAL BACTEREMIA
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DOI：
10.1016/0732-8893(92)90040-z
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发表时间：
1992-02-01
影响因子：
2.9
通讯作者：
BOUZA, E
中科院分区：
文献类型：
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作者：
BERENGUER, J;SAMPEDRO, I;BOUZA, E
c群-溶血性链球菌（GCBHS）是一种罕见的菌血症原因。在5年期间，GCBHS占我院记录的阳性血培养的0.28%和细菌血症的0.35%。GCBHS菌血症的发生率为每1000例入院0.05例。我们分析了13例GCBHS菌血症患者中10例的临床资料。除一人外，所有患者均为患有严重基础疾病的成年人，其中7例为社区获得性发作。只有一例皮肤是入口。临床综合征包括原发性菌血症（4例）、肺炎（2例）、心内膜炎（2例）、脑膜炎、腹内感染和转移性化脓性心包炎（各1例）。在13株分离物中，鉴定到种水平的有12株：6株为均匀链球菌（Streptococcus equissimilis）；3 .马；2 S.泌乳不良；一种是动物流行性链球菌在一株分离物中检测到青霉素耐药性，但我们的分离物均未显示青霉素耐受性。尽管进行了适当的抗菌治疗，但仍有4例患者死亡（40%）。
Group-C beta-hemolytic streptococci (GCBHS) is an uncommon cause of bacteremia. In a 5-year period, GCBHS accounted for 0.28% of positive blood cultures and 0.35% of bacteremias documented at our hospital. The incidence of GCBHS bacteremia was 0.05 episodes per 1000 admissions. We were able to analyze clinical data of 10 of the 13 patients with GCBHS bacteremias. All but one were adults with significant underlying diseases, and seven episodes were community acquired. The skin was the portal of entry in only one case. Clinical syndromes included primary bacteremia (four cases), pneumonia (two cases), endocarditis (two cases), and meningitis, intraabdominal infection, and metastatic suppurative pericarditis (one episode each). Of 13 isolates, 12 were identified to species level: six, Streptococcus equisimilis; three S. equi; two S. dysgalactiae; and one S. zooepidemicus. Resistance to penicillin was detected in one isolate and none of our isolates displayed penicillin tolerance. Four patients died (40%) despite appropriate antimicrobial therapy.