An efficient one-pot procedure for asymmetric bifunctionalization of 5,15-disubstituted porphyrins: a simple preparation of meso acyl-, alkoxycarbonyl-, and carbamoyl-substituted meso-formylporphyrins
An efficient one-pot procedure for asymmetric bifunctionalization of 5,15-disubstituted porphyrins: a simple preparation of meso acyl-, alkoxycarbonyl-, and carbamoyl-substituted meso-formylporphyrins
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DOI：
10.1039/b817551a
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发表时间：
2009-01-01
影响因子：
4.9
通讯作者：
Suda, Kohji
中科院分区：
文献类型：
--
作者：
Takanami, Toshikatsu;Wakita, Atsushi;Suda, Kohji
一种高效的一锅法将5,15-二取代卟啉转化为相应的中甲酰基、烷氧羰基和氨基甲酰取代的中甲酰基卟啉，该方法涉及卟啉与PyMe(2)SiCH(2)Li的顺序S(N)Ar反应，然后是酰化或相关反应和氧化。
An efficient one-pot procedure which converts 5,15-disubstituted porphyrins into their corresponding meso acyl-, alkoxycarbonyl-, and carbamoyl-substituted meso-formylporphyrins has been developed, where the procedure involves a sequential S(N)Ar reaction of porphyrins with PyMe(2)SiCH(2)Li, followed by acylation or related reactions and oxidation.