COTTON DUST AND GRAM-NEGATIVE BACTERIAL-ENDOTOXIN CORRELATIONS IN 2 COTTON TEXTILE MILLS
COTTON DUST AND GRAM-NEGATIVE BACTERIAL-ENDOTOXIN CORRELATIONS IN 2 COTTON TEXTILE MILLS
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DOI：
10.1002/ajim.4700230210
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发表时间：
1993-02-01
影响因子：
3.5
通讯作者：
OLENCHOCK, SA
中科院分区：
文献类型：
--
作者：
CHRISTIANI, DC;WEGMAN, DH;OLENCHOCK, SA
已知接触棉尘可引起急性和慢性呼吸道疾病。在棉花加工（如制纱）行业的工人中，有一种被称为螺旋体病的特殊症状。最近的研究表明革兰氏阴性细菌内毒素是导致急性和可能慢性呼吸道疾病的病原体之一。使用模型室的实验室实验发现，空气中的灰尘和相关的内毒素之间的相关性很差。本文报道了1986年上海两家棉纺织厂11个工作区域的垂直沉降尘和内毒素水平。粉尘与内毒素的总体相关性较强，1号厂和2号厂的r(s)分别为0.66和0.79 （p < 0.0001）。车间前期制纱时粉尘与内毒素的相关性较差，后期制纱区粉尘与内毒素的相关性有所提高。我们的研究结果表明，在这些工厂环境中，大多数工作区域的粉尘和内毒素水平可能很好地相关。因此，粉尘可能是监测全世界棉纺织工业中使用的种群的有用指标。需要进行更多的实地研究，考虑粉尘和内毒素水平的各种决定因素。
Exposure to cotton dust is known to cause both acute and chronic respiratory illness. A specific pattern of symptoms called byssinosis is well described to occur among workers in the cotton processing (e.g., yarn preparation) industry. Recent studies have implicated Gram-negative bacterial endotoxin as one of the agents responsible for acute, and possibly chronic, respiratory illness. Laboratory experiments using a model cardroom have found poor correlations between airborne dust and associated endotoxin. This study reports the results of vertical elutriated dust and endotoxin levels in 11 work areas of 2 cotton textile mills in 1986 in Shanghai, China. The overall correlation between dust and endotoxin was strong, r(s)= 0.66 and 0.79 (p < 0.0001) for mills 1 and 2, respectively. The dust-endotoxin correlation was relatively poor in early yarn preparation in the workshops and improved in the later preparation areas. Our findings suggest that in these mill settings, dust and endotoxin levels may be well correlated in most work areas. Therefore, dust may be a useful index for monitoring populations employed in the cotton textile industry throughout the world. Additional field studies need to be performed which consider the various determinants of dust and endotoxin levels.