A Personal Nanoparticle Respiratory Deposition (NRD) Sampler
A Personal Nanoparticle Respiratory Deposition (NRD) Sampler
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DOI：
10.1021/es201379a
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发表时间：
2011-08-01
影响因子：
11.4
通讯作者：
Peters, Thomas M.
中科院分区：
文献类型：
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作者：
Cena, Lorenzo G.;Anthony, T. Renee;Peters, Thomas M.
开发了一种轻型（60 克）个人纳米颗粒呼吸沉积 (NRD) 采样器，用于选择性收集小于 300 nm 的颗粒，类似于它们在呼吸道中的典型沉积。采样器的运行速度为 2.5 Lpm，由配有冲击器的呼吸式旋风分离器和包含网筛的扩散级组成。冲击器的切点直径确定为 300 nm，锐度 sigma = 1.53。扩散级筛网收集颗粒的效率与呼吸道中小于 300 nm 的颗粒沉积效率相匹配。冲击器分离性能不受典型工作场所水平负载的影响（p 值 = 0.26）。通过对扩散介质进行化学分析，NRD 采样器可用于直接评估除其他空气传播颗粒之外的特定成分纳米颗粒的暴露情况。 NRD 采样器的压降足够低，可以与传统的皮带安装采样泵一起运行。
A lightweight (60 g), personal nanoparticle respiratory deposition (NRD) sampler was developed to selectively collect particles smaller than 300 nm similar to their typical deposition in the respiratory tract. The sampler operates at 2.5 Lpm and consists of a respirable cyclone fitted with an impactor and a diffusion stage containing mesh screens. The cut-point diameter of the impactor was determined to be 300 nm with a sharpness sigma = 1.53. The diffusion stage screens collect particles with an efficiency that matches the deposition efficiency of particles smaller than 300 nm in the respiratory tract. Impactor separation performance was unaffected by loading at typical workplace levels (p-value = 0.26). With chemical analysis of the diffusion media, the NRD sampler can be used to directly assess exposures to nanoparticles of a specific composition apart from other airborne particles. The pressure drop of the NRD sampler is sufficiently low to permit its operation with conventional, belt-mounted sampling pumps.