Improved quantification of radionuclide uptake using deconvolution and windowed subtraction techniques for scatter compensation in single photon emission computed tomography.
Improved quantification of radionuclide uptake using deconvolution and windowed subtraction techniques for scatter compensation in single photon emission computed tomography.
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使用反卷积和窗口减法技术改进放射性核素吸收的量化，以进行单光子发射计算机断层扫描中的散射补偿。
DOI：
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发表时间：
1990
期刊：
影响因子：
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通讯作者：
S. Webb
中科院分区：
文献类型：
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作者：
J. Yanch;M. Flower;S. Webb
本文在定量化改进的基础上，比较了单光子发射计算机断层成像（SPECT）中两种散射补偿方法。方法，散射窗减法和约束反褶积的平均点源响应函数（PSRF），进行了说明，每种方法的理论基础也简要评估。每种方法提供的相对定量的改进是通过检查热圆柱体中计数与轻微放射性背景中计数的比率来测量的。圆柱体/背景浓度比以5倍变化;圆柱体的大小保持不变。保持圆柱体的直径恒定，允许评估浓度差异的影响，而不会产生热源大小变化的冲突影响。结果表明，虽然散射窗口减法和约束反卷积提供量化的改进，在最终的图像，从每个平面投影的平面PSRF的预重建反卷积的方法是实质上更成功的散射窗口减法或其他方法实现的反卷积过程。
A comparison of two methods of scatter compensation in single photon emission computed tomography (SPECT) imaging is made on the basis of improvements in quantification. The methods, scatter-window subtraction and constrained deconvolution of an average point source response function (PSRF), are described; the theoretical basis of each method is also briefly assessed. Improvements in relative quantification offered by each method are measured by examining ratios of counts in hot cylinders to counts in a slightly radioactive background. The cylinder/background concentration ratio was varied by a factor of five; the sizes of the cylinders remained constant. Keeping the diameter of the cylinders constant allowed for an assessment of the effect of concentration differences, without the conflicting effect of variation in the size of the hot source. Results showed that while both scatter-window subtraction and constrained deconvolution offer quantification improvements in the final image, the method of prereconstruction deconvolution of a planar PSRF from each planar projection is substantially more successful than either scatter-window subtraction or other methods of implementing the deconvolution procedure.