Pure mucinous carcinoma of the breast
Pure mucinous carcinoma of the breast
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DOI：
10.1016/j.amjsurg.2003.12.039
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发表时间：
2004-04-01
影响因子：
3
通讯作者：
Schnabel, FR
中科院分区：
文献类型：
--
作者：
Komenaka, IK;El-Tamer, MB;Schnabel, FR
背景：由于缺乏“纯”乳腺粘液癌的标准定义，使得比较不同研究的数据变得困难。本研究使用最严格的标准来定义真正纯粹病变的参数。方法：对65例患者进行分析。该数据库用于评估患者的人口统计学、肿瘤特征和预后。分析生存曲线和生存预测因子。结果：患者平均年龄67岁。大多数（96%）患者表现为早期疾病。5年和10年总生存率分别为93.6%和72.8%。受累腋窝淋巴结数是死亡的唯一显著预测因子（P = 0.02）。结论：单纯乳腺粘液癌预后良好。肿瘤大小似乎不影响生存，可能是因为黏液蛋白的体积高估了肿瘤负荷。受累腋窝淋巴结的数量是疾病死亡的唯一显著预测因子。(C) 2004年摘录医药股份有限公司版权所有。
Background: The lack of a standard definition of "pure" mucinous carcinoma of the breast has made it difficult to compare data from different studies. This study used the most stringent criteria to define parameters for truly pure lesions.Methods: Sixty-five patients were identified. The database was, used to evaluate patients' demographics, tumor characteristics, and outcomes. Survival curves and predictors of survival were analyzed.Results: The mean age of presentation was 67 years. The majority (96%) of patients presented with early-stage disease. The 5- and 10-year overall survival rates were 93.6% and 72.8%, respectively. The number of involved axillary lymph nodes was the only significant predictor of death (P = 0.02).Conclusions: Pure mucinous carcinoma of the breast has a favorable prognosis. Tumor size does not appear to impact survival, perhaps because the volume of mucin overestimates tumor burden. The number of involved axillary lymph nodes was the only significant predictor of death from disease. (C) 2004 Excerpta Medica, Inc. All rights reserved.