Mycobacterium marinum Infections of the Upper Extremity
Mycobacterium marinum Infections of the Upper Extremity
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DOI：
10.1097/01.prs.0000153197.64808.b9
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发表时间：
2005-03-01
影响因子：
3.6
通讯作者：
Murphy, Michael S.
中科院分区：
文献类型：
--
作者：
Hess, Christopher L.;Wolock, Bruce S.;Murphy, Michael S.
大量感染海分枝杆菌的患者在马里兰州巴尔的摩的柯蒂斯国家手部中心接受了治疗。本研究的目的是回顾作者处理上肢海支原体感染的经验。确定了 29 名患者，并审查了他们的图表以了解与诊断和治疗相关的所有因素。最常见的症状是肿胀 (n = 25) 和疼痛 (n = 14)。只有 69% 的患者能够将他们的损伤与水上活动联系起来。从受伤到诊断的平均时间为 5.2 个月。仅 22% 的样本中抗酸杆菌染色呈阳性。平均手术次数为 1.75 次，其中大部分为腱鞘切除术。抗生素治疗的平均持续时间为 6 个月。临床病史、病理评估和高度临床怀疑可以导致早期诊断和使用抗生素。作者的患者通过 6 个月的抗生素治疗和早期手术干预获得了成功治疗。 （塑料重建外科 115：55e，2005 年。）
A significant number of patients infected with Mycobacterium marinum have been treated at the Curtis National Hand Center in Baltimore, Maryland. The purpose of this study was to review the authors' experience with M. marinum infections of the upper extremity. Twenty-nine patients were identified and their charts were reviewed for all factors related to diagnosis and treatment. The most common presenting symptoms were swelling (n = 25) and pain (n = 14). Only 69 percent of patients could correlate their injury with aquatic activities. The mean time from injury to diagnosis was 5.2 months. Acid-fast bacilli stains were positive in only 22 percent of specimens. The mean number of procedures was 1.75, with the majority being tenosynovectomy. The mean duration of antibiotic therapy was 6 months. Clinical history, pathological evaluation, and a high clinical suspicion can lead to early diagnosis and introduction of antibiotics. The authors' patients were successfully treated with 6 months of antibiotic therapy and early surgical intervention. (Plast. Reconstr. Surg. 115: 55e, 2005.)