High precision NOEs as a probe for low level conformers-a second conformation of strychnine
High precision NOEs as a probe for low level conformers-a second conformation of strychnine
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DOI：
10.1039/c0cc04114a
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发表时间：
2011-01-01
影响因子：
4.9
通讯作者：
Harvey, Jeremy N.
中科院分区：
文献类型：
--
作者：
Butts, Craig P.;Jones, Catharine R.;Harvey, Jeremy N.
士的宁的第二构象，具有非常低的人口（2.5%），已被实验确定，并通过计算证实，证明了NOE测量的能力，以区分分钟的贡献，在解决方案中的动态结构合奏。
A second conformer of strychnine, with a very low population (2.5%), has been identified experimentally, and confirmed by computation, demonstrating the ability of NOE measurements to discriminate minute contributions to dynamic structure ensembles in solution.