Functional MR imaging of language, memory, and sensorimotor cortex
Functional MR imaging of language, memory, and sensorimotor cortex
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DOI：
10.1016/j.nic.2004.04.005
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发表时间：
2004-08-01
影响因子：
2.3
通讯作者：
Gaillard, WD
中科院分区：
文献类型：
--
作者：
Gaillard, WD
功能性磁共振成像（fMR成像）用于识别癫痫手术期间保留的功能皮层，主要是初级运动和感觉皮层，以及涉及语言和记忆的脑区。fMR成像语言范例与颈动脉内异戊巴比妥试验（IAT）识别语言优势半球的一致率为90%; 10%的患者出现部分差异;明显的不一致很少见，但可能发生在可识别的情况下。少数直接比较皮层电刺激与fMR成像的研究显示特异性为67%，灵敏度超过90%。记忆范例的fMR成像显示了近中颞叶结构的激活，但尚未验证个体患者手术计划。
Functional magnetic resonance imaging (fMR imaging) is employed to identify eloquent cortex to be spared during epilepsy surgery, principally the primary motor and sensory cortex, and brain areas implicated in language and memory. fMR imaging language paradigms have 90% concordance with intracarotid amobarbital tests (IAT) for identifying the dominant hemisphere for language; partial disparity occurs in 10% of patients; and overt discordance is rare but may occur under recognizable circumstances. The few studies to directly compare electrocortical stimulation with fMR imaging show a specificity of 67% and a sensitivity of over 90%. fMR imaging of memory paradigms demonstrate activation in mesial temporal structures but are not yet validated for individual patient surgical planning.