ASSESSING HEALTH-RELATED QUALITY-OF-LIFE IN PATIENTS WITH SCIATICA
ASSESSING HEALTH-RELATED QUALITY-OF-LIFE IN PATIENTS WITH SCIATICA
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DOI：
10.1097/00007632-199509000-00011
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发表时间：
1995-09-01
期刊：
影响因子：
3
通讯作者：
KELLER, RB
中科院分区：
文献类型：
--
作者：
PATRICK, DL;DEYO, RA;KELLER, RB
研究设计。这项研究分析了来自缅因州腰椎研究的健康相关生活质量测量以及其他临床和问卷数据，该研究是一项针对腰背部问题人群的前瞻性队列研究。对于坐骨神经痛的患者，在3个月的时间里，从内部一致性、结构效度、重复性和检测微小变化的反应性方面，比较了背痛特定的和健康相关的生活质量的一般测量。数据收集自427名患有坐骨神经痛的参与者。在治疗前和治疗后3个月通过邮寄的方式对外科和内科患者进行面对面的基线访谈。与健康相关的生活质量测量包括症状(疼痛和坐骨神经痛的频率和烦扰)、功能状况和幸福感(修改后的背痛特定罗兰量表和医疗结果研究36项简明健康调查(SF-36)，以及残疾(卧床休息、工作减少和限制活动天数)。措施的内部一致性很高。重复性中等，正如预期的那样，间隔3个月后。SF-36身体疼痛项目和改良的罗兰测量显示了最大的变化量，并与自我评估的改善高度相关。具体的和一般性的措施朝着预期的方向变化，但总体健康看法略有下降。临床表现或症状与改良的罗兰测量、SF-36和伤残天数之间的高度相关性表明结构效度很高。这些测量在测量坐骨神经痛患者的健康相关生活质量方面表现良好，改良的罗兰和SF-36的物理维度是对随时间变化最敏感的测量，建议将其用于前瞻性评估。虽然残疾日测量对评估功能障碍的社会影响很有价值，但在这3个月的短期随访中，对变化的反应较小。
Study Design. This study analyzed health-related quality-of-life measures and other clinical and questionnaire data obtained from the Maine Lumbar Spine Study, a prospective cohort study of persons with low back problems.Objective. For persons with sciatica, back pain-specific and general measures of health-related quality-of-life were compared with regard to internal consistency, construct validity, reproducibility, and responsiveness in detecting small changes over a 3-month period.Summary of Background Data. Data were collected from 427 participants with sciatica. Baseline in-person interviews were conducted with surgical and medical patients before treatment and by mail at 3 months.Methods. Health-related quality-of-life measures included symptoms (frequency and bothersomeness of pain and sciatica) functional status and well-being (modified back pain-specific Roland scale and Medical Outcomes Study 36-item Short Form Health Survey (SF-36), and disability (bed rest, work loss, and restricted activity days).Results. Internal consistency of measures was high. Reproducibility was moderate, as expected after a 3-month interval. The SF-36 bodily pain item and the modified Roland measure demonstrated the greatest amount of change and were the most highly associated with self-rated improvement. The specific and generic measures changed in the expected direction, except for general health perceptions, which declined slightly. A high correlation between clinical findings or symptoms and the modified Roland measure, SF-36, and disability days indicated a high degree of construct validity.Conclusions. These measures performed well in measuring the health-related quality-of-life of patients with sciatica, The modified Roland and the physical dimension of the SF-36 were the measures most responsive to change over time, suggesting their use in prospective evaluation. Disability day measures, although valuable for assessing the societal impact of dysfunction, were less responsive to changes over this short-term follow-up of 3 months.