Social perception as a mediator of the influence of early visual processing on functional status in schizophrenia

Social perception as a mediator of the influence of early visual processing on functional status in schizophrenia
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DOI:
10.1176/appi.ajp.163.3.448
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发表时间:
2006-03-01
影响因子:
17.7
通讯作者:
Green, MF
Green, MF
中科院分区:
医学1区
文献类型:
--
作者:
Sergi, MJ;Rassovsky, Y;Green, MF

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目的:神经认知与社会认知或社会认知与功能状态的相关研究表明,社会认知可能是精神分裂症患者神经认知与功能状态之间关系的中介。作者使用结构方程模型来更直接地检验社会认知的一个方面(社会知觉)是否介导了精神分裂症患者基本视觉知觉与功能状态之间的关系。方法:对75例精神分裂症门诊患者进行早期视觉加工(计算机化视觉掩蔽程序)、社会知觉(非语言敏感性半剖面)和功能状态(角色功能量表)测量。结果:结构方程模型支持社会知觉作为精神分裂症早期视觉加工和功能状态之间关系的中介。中介模型表明,早期视觉加工通过社会知觉与功能状态相关联,从而支持一个重要的间接关系。在不包含社会知觉的模型中,早期视觉加工与功能状态的直接关系显著,而在包含社会知觉的中介模型中,早期视觉加工与功能状态的直接关系不显著。结论:社会认知似乎是精神分裂症功能状态的关键决定因素。本研究使用一种非常基本的视觉知觉测量,发现社会知觉介导了早期视觉加工对精神分裂症功能状态的影响。
Objective: The potential of social cognition as a mediator of relations between neurocognition and functional status in schizophrenia has been suggested by correlational studies that link neurocognition to social cognition or link social cognition to functional status. The authors used structural equation modeling to test more directly whether one aspect of social cognition (social perception) mediates relations between basic visual perception and functional status in patients with schizophrenia.Method: Seventy-five outpatients with schizophrenia were administered measures of early visual processing (computerized visual masking procedures), social perception (Half Profile of Nonverbal Sensitivity), and functional status (Role Functioning Scale).Results: Structural equation modeling supported social perception as a mediator of relations between early visual processing and functional status in schizophrenia. The mediation model indicated that early visual processing is linked to functional status through social perception, thereby supporting a significant indirect relationship. The direct relationship between early visual processing and functional status was significant in a model that did not include social perception but was not significant in the mediation model that included social perception.Conclusions: Social cognition appears to be a key determinant of functional status in schizophrenia. Using a very basic measure of visual perception, the present study found that social perception mediates the influence of early visual processing on functional status in schizophrenia.