Fibrosing cholestatic hepatitis after liver transplantation in a patient with hepatitis C and HIV infection.
Fibrosing cholestatic hepatitis after liver transplantation in a patient with hepatitis C and HIV infection.
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丙型肝炎和 HIV 感染患者肝移植后纤维化胆汁淤积性肝炎。
DOI：
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发表时间：
2001
影响因子：
158.5
通讯作者：
C. Millson
中科院分区：
文献类型：
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作者：
D. Tolan;M. Davies;C. Millson
致编者：由于同时感染乙型肝炎病毒（HBV）、丙型肝炎病毒（HCV）或两者的并发症，少数但越来越多的人类免疫缺陷病毒（HIV）感染患者接受原位肝移植。HCV总是再次感染同种异体肝脏移植物，通常引起小叶性肝炎，并且在短期内耐受性相当好。如果乙肝在移植后复发，通常会导致破坏性疾病，其特征是迅速进展的病理过程，称为纤维化胆汁淤积性肝炎，导致肝功能衰竭1这一过程的假设机制是在移植受体中免疫抑制介导的无阻碍病毒复制。艾滋病毒有……
To the Editor: A small but growing number of patients with human immunodeficiency virus (HIV) infection undergo orthotopic liver transplantation for complications of intercurrent infection with hepatitis B virus (HBV), hepatitis C virus (HCV), or both. HCV invariably reinfects liver allografts, typically causing a lobular hepatitis, and is reasonably well tolerated in the short term. If hepatitis B recurs after transplantation, it frequently causes devastating disease characterized by a rapidly progressive pathological process termed fibrosing cholestatic hepatitis, resulting in liver failure.1 The postulated mechanism of this process is unimpeded viral replication mediated by immunosuppression in the transplant recipient. HIV has . . .
影响因子：
6.2
作者：
C. M. Toth;M. Pascual;R. Chung;F. Graeme-Cook;J. Dienstag;A. Bhan;A. Cosimi
通讯作者：
C. M. Toth;M. Pascual;R. Chung;F. Graeme-Cook;J. Dienstag;A. Bhan;A. Cosimi