VASCULAR CHANGES IN THE CHEEK POUCH OF THE GOLDEN HAMSTER DURING INFECTION WITH TRICHINELLA-SPIRALIS LARVAE
VASCULAR CHANGES IN THE CHEEK POUCH OF THE GOLDEN HAMSTER DURING INFECTION WITH TRICHINELLA-SPIRALIS LARVAE
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DOI：
10.1002/ar.1091140108
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发表时间：
1952-01-01
影响因子：
--
通讯作者：
AKERS, RP
中科院分区：
文献类型：
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作者：
HUMES, AG;AKERS, RP
对感染旋毛虫的金黄地鼠颊囊的活体观察显示，在感染后的头几周，小静脉和静脉中有粘性的白细胞和白细胞铺面。到了第5周，形成的元素开始恢复正常流动。这种炎症反应的证据与肠道内成虫产生幼虫的时间非常吻合。小动脉内的血流仍然畅通。横纹肌纤维中的幼虫早在感染后第19天就被明显的静脉血管网络包围，在体外或通过铬酸铅的血管内沉淀很容易观察到。这些血管呈窦状，早期管腔较大，由一条或多条小动脉发出。错综复杂的分支、环和吻合口没有固定的模式，尽管经常有明显的血管横跨囊肿轴。网状血管从幼虫附近排出，形成一个或多个小静脉。差不多一年了。感染后网状血管直径变小。而且数量明显较少，整个网络相对不起眼。
Observations in vivo on the cheek pouches of hamsters infected with T. spiralis showed sticky leukocytes and leukocytic pavements in the venules and veins during the first few weeks after infection. By the 5th week the formed elements began to regain their normal flow. This evidence of an inflammatory reaction coincided rather closely with the time when larvae were presumably being produced by the adult worms in the intestine. Blood flow remained unobstructed in the arterioles. The larvae in the striated muscle fibers became surrounded as early as the 19th day after infection by a conspicuous vascular network of venous vessels, easily observed in vitro or by the intravascular precipitation of lead chromate. These vessels appeared to be sinusoid, with larger lumina in early stages than at later times, and arose from one or more arterioles. The intricate branches, loops, and anastomoses did not have a fixed pattern although frequently there were conspicuous vessels running transversely across the axis of the cyst. The network vessels drained away from the vicinity of the larva into one or more venules. Nearly one yr. after infec-tion the vessels of the network were smaller in diam. and apparently fewer in number, with the whole network relatively inconspicuous.