Boronic acid substituted viologen based optical sugar sensors: modulated quenching with viologen as a method for monosaccharide detection

Boronic acid substituted viologen based optical sugar sensors: modulated quenching with viologen as a method for monosaccharide detection
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DOI:
10.1016/s0040-4039(01)02366-8
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发表时间:
2002-02-11
影响因子:
1.8
通讯作者:
Singaram, B
Singaram, B
中科院分区:
化学4区
文献类型:
--
作者:
Camara, JN;Suri, JT;Singaram, B

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在我们对光学葡萄糖传感器的研究中,我们发现吡喃I和硼酸取代的苄基紫精(o-BBV)的组合。2)单糖信号在0 - 1800 mg/dL的范围内。o-BBV的淬灭能力在糖结合后被调节。这又改变了吡喃的荧光。该系统利用的染料是在可见光谱中的活性,在pH 7.4的水溶液中操作,并在生理范围内对葡萄糖高度敏感。(C)2002爱思唯尔科技有限公司。保留所有权利。
In our search for an optical glucose sensor we have found that the combination of pyranine I and a boronic acid substituted benzyl viologen (o-BBV. 2) signals in monosaccharides in the range of 0 1800 mg/dL. The quenching ability of o-BBV is modulated upon sugar binding. which in turn alters the fluorescence of pyranine. The system utilizes a dye that is active in the visible spectrum, operates in aqueous solution at pH 7.4, and is highly sensitive to glucose in the physiological range. (C) 2002 Elsevier Science Ltd. All rights reserved.