Three-dimensional printing-based personalized limb salvage and reconstruction treatment of pelvic tumors
Three-dimensional printing-based personalized limb salvage and reconstruction treatment of pelvic tumors
复制标题
基于三维打印的盆腔肿瘤个性化保肢重建治疗
DOI：
10.1002/jso.26516
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发表时间：
2021-06-04
影响因子：
2.5
通讯作者：
Hao, Yongqiang
中科院分区：
文献类型：
--
作者：
Wu, Junxiang;Xie, Kai;Hao, Yongqiang
背景和目的盆腔肿瘤的治疗被广泛认为是具有挑战性的。本研究的目的是评估基于个性化三维打印的骨盆肿瘤保肢重建治疗的疗效。准备3D打印病变模型和截骨模板，用于手术计划、假体设计和手术期间的截骨辅助。基于3D打印的个性化骨盆假体被制造并用于所有28名患者。结果平均随访32.2个月，16例无瘤生存，3例带瘤生存，9例死亡。假体稳定，旋转中心平均偏移5.48 mm，假体-骨界面结合良好。对于19名存活患者，平均MSTS下肢功能评分为23.2。术后并发症包括浅表感染6例，髋关节脱位3例。结论基于3D打印的个性化保肢重建是治疗盆腔肿瘤的有效方法。我们的患者取得了良好的术后早期疗效和功能恢复。
Background and Objectives The treatment of pelvic tumors is widely recognized to be challenging. The purpose of this study was to evaluate the efficacy of personalized three-dimensional (3D) printing-based limb salvage and reconstruction treatment for pelvic tumors.Methods Twenty-eight pelvic tumor patients were enrolled. 3D printing lesion models and osteotomy templates were prepared for surgery planning, prosthesis design, and osteotomy assistance during surgery. 3D printing-based personalized pelvic prostheses were manufactured and used in all 28 patients. Follow-up of postoperative survival, prosthesis survival, imaging examinations, and Musculoskeletal Tumor Society (MSTS) lower limb functional scores were carried out.Results The mean follow-up period was 32.2 months, during which 16 patients had disease-free survival, 3 survived with the disease, and 9 died. The prostheses were stable, and the mean offset of the center of rotation was 5.48 mm. The prosthesis-bone interface showed good integration. For the 19 surviving patients, the mean MSTS lower limb functional score was 23.2. Postoperative complications included superficial infection in six patients and hip dislocation in three patients.Conclusions Personalized 3D printing-based limb salvage and reconstruction was an effective treatment for pelvic tumors. Our patients achieved good early postoperative efficacy and functional recovery.