Obesity and the risk of new-onset atrial fibrillation
Obesity and the risk of new-onset atrial fibrillation
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DOI：
10.1001/jama.292.20.2471
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发表时间：
2004-11-24
影响因子：
120.7
通讯作者：
Benjamin, EJ
中科院分区：
文献类型：
--
作者：
Wang, TJ;Parise, H;Benjamin, EJ
肥胖与心房扩大和心室舒张功能障碍有关，这两者都是已知的心房颤动（AF）的预测因子。然而，肥胖是否是af的危险因素尚不清楚。为了研究身体质量指数（BMI）与发生心房纤颤风险之间的关系。设计、设置和参与者：来自马萨诸塞州弗雷明汉的前瞻性社区观察队列。我们研究了5282名无基线房颤（心电图房颤或动脉扑动）的参与者（平均年龄57 [SD， 13]岁；2898名女性[55%]）。体重指数（以体重（公斤）除以身高（米）的平方计算）被评估为连续变量和分类变量(通常定义为
Context Obesity is associated with atrial enlargement and ventricular diastolic dysfunction, both known predictors of atrial fibrillation (AF). However, it is unclear whether obesity is a risk factor for AF.Objective. To examine the association between body mass index (BMI) and the risk of developing AF.Design, Setting, and Participants Prospective, community-based observational cohort in Framingham, Mass. We studied 5282 participants (mean age, 57 [SD, 13] years; 2898 women [55%]) without baseline AF (electrocardiographic AF or arterial flutter). Body mass index (calculated as weight in kilograms divided by square of height in meters) was evaluated as both a continuous and a categorical variable (normal defined as