New Insulin Infusion Protocol Improves Blood Glucose Control in Hospitalized Patients Without Increasing Hypoglycemia
New Insulin Infusion Protocol Improves Blood Glucose Control in Hospitalized Patients Without Increasing Hypoglycemia
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DOI：
10.1016/s1553-7250(05)31019-1
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发表时间：
2005-03-01
影响因子：
2.3
通讯作者：
Kelly, Janet L.
中科院分区：
文献类型：
--
作者：
Ku, Susanna Y.;Sayre, Cindy A.;Kelly, Janet L.
背景：积极治疗住院患者的高血糖可以改善重要的临床预后。在华盛顿大学医学中心开展了一项质量改进项目，以制定和实施在整个机构使用的标准化胰岛素输注方案。方法：胰岛素输注方案在重症和非重症住院病房试行。每个单位收集了一个月的安全性和有效性数据。结果：共评估了156例患者。研究组低血糖的发生率低于历史对照组，患者高血糖的平均时间百分比也低于历史对照组，重症监护亚组为15% +/- 2.3%，而非重症监护亚组为33% +/- 2.6% (p < 0.0001), 18% +/- 2.4%，非重症监护亚组为56% +/- 2.3% （p < 0.0001）
Background: Aggressive treatment of hyperglycemia in hospitalized patients can improve clinically important outcomes. At the University of Washington Medical Center a quality improvement project was conducted to develop and implement a standardized insulin infusion protocol for use throughout the institution.Methods: The insulin infusion protocol was piloted on critical and non-critical care inpatient units. Safety and efficacy data were collected for a one-month period on each unit.Results: A total of 156 patients were evaluated. The incidence of hypoglycemia was lower for the study group than the historical controls, as was the mean percentage of time patients were hyperglycemic, 15% +/- 2.3% vs. 33% +/- 2.6% for the critical care subgroup (p < .0001) and 18% +/- 2.4% vs. 56% +/- 2.3% for the non-critical care subgroup (p