Extracellular Vesicles as Biomarkers in Cardiovascular Disease; Chances and Risks.
Extracellular Vesicles as Biomarkers in Cardiovascular Disease; Chances and Risks.
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DOI:
10.3389/fcvm.2018.00113
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发表时间:
2018
影响因子:
3.6
通讯作者:
Koenen RR
中科院分区:
文献类型:
--
作者:
Dickhout A;Koenen RR
The field of extracellular vesicles (EV) is rapidly expanding, also within cardiovascular diseases. Besides their exciting roles in cell-to-cell communication, EV have the potential to serve as excellent biomarkers, since their counts, content, and origin might provide useful information about the pathophysiology of cardiovascular disorders. Various studies have already indicated associations of EV counts and content with cardiovascular diseases. However, EV research is complicated by several factors, most notably the small size of EV. In this review, the advantages and drawbacks of EV-related methods and applications as biomarkers are highlighted.
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DOI:
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发表时间:
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期刊:
Journal of thrombosis and haemostasis : JTH
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