Visually-guided correction of hand reaching movements: The neurophysiological bases in the cerebral cortex
Visually-guided correction of hand reaching movements: The neurophysiological bases in the cerebral cortex
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DOI：
10.1016/j.visres.2014.09.009
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发表时间：
2015-05-01
期刊：
影响因子：
1.8
通讯作者：
Battaglia-Mayer, A.
中科院分区：
文献类型：
--
作者：
Archambault, P. S.;Ferrari-Toniolo, S.;Battaglia-Mayer, A.
人类和非人类灵长类动物在目标位置突然移动后对手部运动轨迹进行快速校正的能力是视觉运动行为的一个关键特征。在健康个体中，手部运动平滑地适应目标位置的变化，而不需要像顶骨患者那样完成到第一目标位置的运动。这一发现表明，神经系统持续监测视觉场景，并能够整合新的信息，以产生有效的运动反应。在本文中，我们回顾了运动学，反应时间和肌肉活动的在线校正的手的动作，以及通过单细胞神经记录在猴子研究的基础神经生理过程中观察到的。脑刺激，病变和成像研究在人类也进行了讨论。我们证明，虽然在线校正机制强烈依赖于顶叶-额叶网络的活动，其中后顶叶皮层是一个关键节点，这些机制顺利进行，并在简单的点对点运动中观察到的相似。手部动作的在线校正将依赖于顶叶皮层中的前馈和反馈机制，作为额顶叶网络内用于规划和执行视觉运动任务的活动的一部分。(C)2014爱思唯尔有限公司版权所有。
The ability of human and non-human primates to make fast corrections to hand movement trajectories after a sudden shift in the target's location is a key feature of visuo-motor behavior. In healthy individuals, hand movements smoothly adapt to a change in target location without needing to complete the movement to the first target location, as typical of parietal patients. This finding indicates that the nervous system continuously monitors the visual scene and is able to integrate new information in order to produce an efficient motor response. In this paper, we review the kinematics, reaction times and muscle activity observed during the online correction of hand movements as well as the underlying neurophysiological processes studied through single-cell neural recordings in monkeys. Brain stimulation, lesion and imaging studies in humans are also discussed. We demonstrate that while online correction mechanisms strongly depend on the activity of a parieto-frontal network of which the posterior parietal cortex is a crucial node, these mechanisms proceed smoothly and are similar to what is observed during simple point-to-point movements. Online correction of hand movements would rely on feedforward and feedback mechanisms in the parietal cortex, as part of the activity within the fronto-parietal network for the planning and execution of visuo-motor tasks. (C) 2014 Elsevier Ltd. All rights reserved.